Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064558 | 0.86 | TRPA1 (0.62) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL28238190 | 0.86 | TRPA1 (0.62) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL27536509 | 0.82 | TYR (0.52) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL27766136 | 0.82 | TRPA1 (0.45) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL28150359 | 0.80 | TRPA1 (0.84) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Sulfuric Acid SCHEMBL11109027 | 0.79 | LMNA (0.53) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL22165 | 0.79 | LMNA (1.00) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL51957 | 0.79 | LMNA (0.75) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL29579824 | 0.79 | LMNA (1.00) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL30332213 | 0.79 | LMNA (1.00) | TRPA1LMNACHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330675-A | Inhibitors of HIV replication | VIIV HEAL THCARE UK LTD | 2016-02-17 | — | — | CN | disclosed |
| CN-103429595-B | Inhibitors of HIV Replication | VIIV HEALTHCARE UK LTD. (GB) | 2015-10-21 | — | — | CN | disclosed |
| CN-103429595-A | Inhibitors of hiv replication | VIIV HEALTHCARE UK LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-101855224-B | Equilibrative nucleoside transporter ENT1 inhibitors | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | disclosed |
| CN-101855224-A | Equilibrative nucleoside transporter ENT 1 inhibitors | JANSSEN PHARMACEUTICA NV | 2010-10-06 | — | — | CN | disclosed |
| CN-101146798-A | Novel heterocyclic benzo[C]chromene derivatives useful as modulators of the estrogen receptors | JANSSEN PHARMACEUTICA NV (BE) | 2008-03-19 | — | — | CN | disclosed |