Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30300424 | 0.88 | NOTUM (0.62) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4652262 | 0.86 | BRD4 (0.54) | RAB9ANPC1MEN1KMT2AMAOA | |
| SCHEMBL14022344 | 0.83 | KMT2A (0.57) | RAB9AMEN1KMT2ASMN1; SMN2BRD4 | |
| SCHEMBL27697703 | 0.83 | NPC1 (0.59) | RAB9ANPC1MEN1KMT2AMAOA | |
| SCHEMBL20524671 | 0.80 | NOTUM (0.56) | RAB9ANPC1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL30323171 | 0.80 | NOTUM (0.56) | RAB9ANPC1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL19538829 | 0.78 | MAPT (0.61) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL14887585 | 0.77 | PTPRC (0.53) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL16017249 | 0.75 | LMNA (0.53) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL1488991 | 0.74 | NOTUM (0.48) | BRD4CREBBPNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101052634-B | Anthranilamide pyridinureas as vegf receptor kinase inhibitors | BAYER SCHERING PHARMA AG | 2011-05-18 | — | — | CN | disclosed |
| CN-101052634-A | Anthranilamide pyridinureas as vegf receptor kinase inhibitors | BAYER SCHERING PHARMA AG (DE) | 2007-10-10 | — | — | CN | disclosed |