SCHEMBL27698252

SCHEMBL27698252

Cc1ccc(-c2ccc(Cl)cc2)cc1C1C(=O)OC(C)(C)C(C)(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.39
ACACB O00763 6/20 0.34
ACACA Q13085 6/20 0.34
NOTUM Q6P988 1/20 0.31
TDP2 O95551 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1550368 0.79 PGR (0.42) PGRACACBACACATDP2HDAC1
SCHEMBL11025445 0.74 ACACB (0.38) PGRACACBACACATDP2
SCHEMBL1550846 0.73 PGR (0.38) PGRACACBACACATDP2HDAC1
SCHEMBL2363323 0.72 PGR (0.37) PGRACACBACACANOTUM
SCHEMBL3018648 0.71 ACACB (0.36) PGRACACBACACATDP2HDAC1
SCHEMBL3018651 0.71 ACACB (0.36) PGRACACBACACATDP2HDAC1
SCHEMBL2362821 0.71 KDM4E (0.36) ACACBACACANOTUM
SCHEMBL9110791 0.68 CYP3A4 (0.33) PGRACACBACACANOTUMTDP2
SCHEMBL2362432 0.68 ACACB (0.34) PGRACACBACACATDP2
SCHEMBL2677397 0.68 ACACB (0.41) PGRACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101010306-A Phenyl-substituted [1.2] -oxazine-3, 5-dione and dihydropyrone derivatives BAYER CROPSCIENCE AG (DE) 2007-08-01 CN disclosed