Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL440991 | 1.00 | — | — | |
| Acetic Acid SCHEMBL11324300 | 0.96 | — | — | |
| Butadiene SCHEMBL7066120 | 0.93 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL5928939 | 0.93 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetone SCHEMBL28253462 | 0.88 | — | — | |
| Maleic Acid SCHEMBL28090059 | 0.87 | TSHR (0.53) | FFAR3LCKFYNALDH1A1LMNA | |
| Methacrylic Acid SCHEMBL10810784 | 0.87 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL28090276 | 0.87 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL27945318 | 0.85 | FFAR3 (0.39) | FFAR3LCKFYNALDH1A1LMNA | |
| Bicarbonate SCHEMBL95086 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100520603-C | Electrophotoconductor and image forming apparatus | SHARP KK (JP) | 2009-07-29 | — | — | CN | disclosed |
| CN-101030050-A | Electrophotoconductor and image forming apparatus | SHARP KK (JP) | 2007-09-05 | — | — | CN | disclosed |