Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL440991 | 0.87 | — | — | |
| Acetic Acid SCHEMBL27698447 | 0.87 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL11324300 | 0.84 | — | — | |
| Acrylic Acid SCHEMBL15676628 | 0.82 | LMNA (0.59) | FFAR3LCKFYNALDH1A1LMNA | |
| Acrylic Acid SCHEMBL28779748 | 0.82 | LMNA (0.59) | FFAR3LCKFYNALDH1A1LMNA | |
| Acrylic Acid SCHEMBL29058085 | 0.82 | LMNA (0.59) | FFAR3LCKFYNALDH1A1LMNA | |
| Butadiene SCHEMBL7066120 | 0.81 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL5928939 | 0.81 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL25333160 | 0.81 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL21961942 | 0.81 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103351758-B | Primer coating compositions for polypropylene substrate and preparation method thereof | 比亚迪股份有限公司 | 2016-07-27 | — | — | CN | disclosed |