Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092297 | 0.76 | MGLL (0.44) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9354495 | 0.74 | SPHK2 (0.50) | MEN1KMT2APOLBL3MBTL1SPHK2 | |
| SCHEMBL9358849 | 0.74 | SPHK2 (0.50) | MEN1KMT2APOLBL3MBTL1SPHK2 | |
| SCHEMBL9354505 | 0.74 | SPHK2 (0.50) | MEN1KMT2APOLBL3MBTL1SPHK2 | |
| SCHEMBL8425723 | 0.74 | MGLL (0.33) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL4565485 | 0.72 | HTT (0.43) | SMN1; SMN2DPP4 | |
| SCHEMBL5267939 | 0.71 | SPHK2 (0.58) | KMT2AL3MBTL1SPHK2SMN1; SMN2 | |
| SCHEMBL4602602 | 0.71 | SPHK2 (0.58) | KMT2AL3MBTL1SPHK2SMN1; SMN2 | |
| SCHEMBL809494 | 0.71 | SPHK2 (0.58) | KMT2AL3MBTL1SPHK2SMN1; SMN2 | |
| SCHEMBL9354526 | 0.70 | SPHK2 (0.52) | KMT2AL3MBTL1SPHK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137621-A | Pyrrolidine derivative intermediate, preparation method and application thereof | CHENGDU DII AO JIUHONG PHARMAC (CN) | 2008-03-05 | — | — | CN | disclosed |