Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680103 | 0.77 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL3483440 | 0.74 | LTB4R2 (0.50) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL3483338 | 0.72 | MEN1 (0.70) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8761451 | 0.71 | MEN1 (0.54) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL3482860 | 0.70 | LTB4R2 (0.56) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL3483620 | 0.68 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL1416009 | 0.68 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL1068790 | 0.68 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL3483115 | 0.67 | MEN1 (0.73) | KMT2AMEN1ALDH1A1GLATSHR | |
| SCHEMBL3483439 | 0.67 | THRB (0.54) | KMT2AALDH1A1GLATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103211811-B | Stable pharmaceutical composition | ASAHI KASEI PHARMA CORP | 2015-06-10 | — | — | CN | disclosed |
| CN-103211811-A | Stable pharmaceutical composition | ASAHI KASEI PHARMA CORP | 2013-07-24 | — | — | CN | disclosed |
| CN-101932317-B | Stable pharmaceutical composition | ASAHI KASEI PHARMA CORP | 2013-03-27 | — | — | CN | disclosed |
| CN-101932317-A | Stable pharmaceutical composition | ASAHI KASEI PHARMA CORP | 2010-12-29 | — | — | CN | disclosed |
| CN-101031539-A | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHAMA CORP (JP) | 2007-09-05 | — | — | CN | disclosed |