Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.66 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.65 |
| ▸ | ALPI | P09923 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | XIAP | P98170 | 1/20 | 0.65 |
| ▸ | LTA4H | P09960 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27654977 | 0.88 | ITGB3 (0.77) | ITGB3ITGA2BSLC7A5ALPIPKM | |
| SCHEMBL4933164 | 0.86 | FFAR1 (0.59) | ITGB3ITGA2BFFAR1LTA4HNPC1 | |
| SCHEMBL4933170 | 0.86 | FFAR1 (0.59) | ITGB3ITGA2BFFAR1LTA4HNPC1 | |
| SCHEMBL27674868 | 0.86 | ITGB3 (0.80) | ITGB3ITGA2BSLC7A5ALPIPKM | |
| SCHEMBL12379308 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2BFFAR1SLC7A5ALPI | |
| SCHEMBL288912 | 0.85 | SLC7A5 (0.69) | ITGB3ITGA2BFFAR1SLC7A5ALPI | |
| SCHEMBL515522 | 0.85 | SLC7A5 (0.69) | ITGB3ITGA2BFFAR1SLC7A5ALPI | |
| SCHEMBL659105 | 0.85 | SLC7A5 (0.69) | ITGB3ITGA2BFFAR1SLC7A5ALPI | |
| SCHEMBL6474836 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BFFAR1SLC7A5ALPI | |
| SCHEMBL14967446 | 0.84 | SLC7A5 (0.85) | FFAR1SLC7A5ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101142228-A | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | POLYPHOR LTD (CH) | 2008-03-12 | — | — | CN | disclosed |