SCHEMBL288912

SCHEMBL288912

N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.69
ALPI P09923 1/20 0.69
PKM P14618 1/20 0.69
PTGS1 P23219 1/20 0.69
XIAP P98170 1/20 0.69
PPARG P37231 4/20 0.65
PPARA Q07869 3/20 0.65
LTA4H P09960 7/20 0.64
LAP3 P28838 1/20 0.64
ITGB3 P05106 1/20 0.61
ITGA2B P08514 1/20 0.61
FFAR1 O14842 1/20 0.60
FFAR4 Q5NUL3 1/20 0.60
MEN1 O00255 1/20 0.58
HSP90AA1 P07900 1/20 0.58
HSP90AB1 P08238 1/20 0.58
PLA2G2A P14555 1/20 0.58
KMT2A Q03164 1/20 0.58
MAOB P27338 1/20 0.58
PARP10 Q53GL7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659105 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL515522 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL4757532 0.98 SLC7A5 (0.67) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL16816702 0.98 SLC7A5 (0.67) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL6065556 0.98 SLC7A5 (0.67) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL16816706 0.98 SLC7A5 (0.67) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL12379285 0.96 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Trifluoroacetic Acid SCHEMBL8208389 0.93 PTPN1 (0.63) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL21340321 0.92 ITGB3 (0.60) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine Methyl Ester SCHEMBL28633098 0.91 LTA4H (0.70) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534498-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-01-27 US claimed
US-20250353814-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS OHIO STATE INNOVATION FOUNDATION (US) 2025-11-20 US claimed
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-11-06 US claimed
EP-4626908-A1 PEPTIDES CAPABLE OF INHIBITING PROTEIN-PROTEIN INTERACTIONS AT GABA-B1A SUBUNIT AND USES THEREOF University of Copenhagen (DK) 2025-10-08 EP claimed
US-12404236-B2 Non-peptidic cell-penetrating motifs OHIO STATE INNOVATION FOUNDATION (US) 2025-09-02 US claimed
US-12329799-B2 Peptidyl inhibitors of calcineurin-NFAT interaction OHIO STATE INNOVATION FOUNDATION (US) 2025-06-17 US claimed
CN-119390963-B Polypeptide ester ether amine random polymer and preparation method and application thereof 浙江大学 2025-04-29 CN claimed
CN-119390963-A Polypeptide ester ether amine random polymer and preparation method and application thereof 浙江大学 2025-02-07 CN claimed
EP-4448544-A2 CARBONIC ANHYDRASE IX LIGANDS 3B Pharmaceuticals GmbH (DE) 2024-10-23 EP claimed
CN-114457049-B Pyrrolysiyl-tRNA synthetase mutant and application thereof 浙江大学杭州国际科创中心 2024-09-24 CN claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed
EP-0217804-A1 ANALOGS OF SUBSTANCES P. ENICHEM SPA (IT) 1987-04-15 EP claimed
US-4638046-A Retro-inverso C-terminal hexapeptide analogues of substance P ENI-ENTE NAZIONALE IDROCARBURI (IT) 1987-01-20 US claimed
WO-1986003495-A2 DERIVATIVES OF SUBSTANCES P AND OF FRAGMENTS THEREOF ENICHEM S.P.A. (IT) 1986-06-19 WO claimed
EP-0161007-A2 Retro - inverso C-Terminal hexapeptide analogues of substance P ENI-Ente Nazionale Idrocarburi (IT) 1985-11-13 EP claimed
EP-0082568-B1 RETRO-INVERSO ANALOGUES OF C-TERMINAL PENTA AND HEXAPEPTIDES OF SUBSTANCE P. ANIC S.p.A. (IT) 1984-11-21 EP claimed
US-4483807-A Process for producing a slow release composite JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1984-11-20 US claimed
EP-0036713-B1 ANGIOTENSIN CONVERTING ENZYME INHIBITORS UNIVERSITY OF MIAMI (US) 1984-01-18 EP claimed
EP-0082568-A2 Retro-inverso analogues of C-terminal penta and hexapeptides of substance P. ANIC S.p.A. (IT) 1983-06-29 EP claimed
US-3936469-A Process for preparing N-carboxylic anhydrides of amino acids KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JA) 1976-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404236-B2 Non-peptidic cell-penetrating motifs TIMM50, TIMM10, PITRM1 SLC7A5 293/4885ALPI 4656/4885PKM 1287/4885
US-20250353814-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS TIMM50, TIMM10, PITRM1 SLC7A5 293/4885ALPI 4656/4885PKM 1287/4885
US-12534498-B2 Compounds for use as apelin receptor antagonists APLNR, NPBWR1, AP3B1 SLC7A5 437/4885ALPI 1616/4885PKM 1555/4885
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS CA9, CA13, CA4 SLC7A5 780/4885ALPI 150/4885PKM 2993/4885
US-12329799-B2 Peptidyl inhibitors of calcineurin-NFAT interaction CHP1, NFATC1, PPP3R1 SLC7A5 3504/4885ALPI 4341/4885PKM 3842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.