⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28769 | 0.97 | — | — | |
| SCHEMBL28768 | 0.97 | — | — | |
| SCHEMBL7286617 | 0.92 | FAAH (0.48) | — | |
| SCHEMBL7287333 | 0.92 | TRPV1 (0.48) | — | |
| SCHEMBL7286614 | 0.92 | FAAH (0.48) | — | |
| SCHEMBL7348367 | 0.92 | TRPV1 (0.48) | — | |
| SCHEMBL28822 | 0.88 | — | — | |
| SCHEMBL28821 | 0.88 | — | — | |
| SCHEMBL129255 | 0.86 | FAAH (0.61) | — | |
| SCHEMBL131304 | 0.86 | FAAH (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103990111-A | Methods for attenuating release of inflammatory mediators and peptides useful therein | BIOMARCK PHARMACEUTICALS LTD | 2014-08-20 | — | — | CN | disclosed |
| CN-101516190-B | Methods for reducing inflammatory mediator release and peptides useful therefor | BIOMARCK PHARMACEUTICALS LTD | 2014-06-11 | — | — | CN | disclosed |
| CN-101146545-B | Mucin hypersecretion inhibitors based on the structure of MANS and methods of use | BIOMARCK PHARMACEUTICALS LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-101516190-A | Methods for reducing inflammatory mediator release and peptides useful therefor | BIOMARCK PHARMACEUTICALS LTD (US) | 2009-08-26 | — | — | CN | disclosed |
| CN-101146545-A | Mucin hypersecretion inhibitors based on the structure of MANS and methods of use | BIOMARCK PHARMACEUTICALS LTD (US) | 2008-03-19 | — | — | CN | disclosed |