⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28769 | 1.00 | — | — | |
| Methane SCHEMBL27699324 | 0.97 | — | — | |
| SCHEMBL7286617 | 0.94 | FAAH (0.48) | — | |
| SCHEMBL7287333 | 0.94 | TRPV1 (0.48) | — | |
| SCHEMBL7286614 | 0.94 | FAAH (0.48) | — | |
| SCHEMBL7348367 | 0.94 | TRPV1 (0.48) | — | |
| SCHEMBL28822 | 0.91 | — | — | |
| SCHEMBL28821 | 0.91 | — | — | |
| SCHEMBL131304 | 0.88 | FAAH (0.61) | — | |
| SCHEMBL450162 | 0.88 | FAAH (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2736 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402124-A | Aryl sulfonamide compound and anti-influenza application thereof | 中国医学科学院医药生物技术研究所 | 2024-01-16 | — | — | CN | claimed |
| CN-110997891-B | Cleaning compositions comprising alkoxylated esteramines | 宝洁公司 | 2021-05-07 | — | — | CN | claimed |
| CN-110997891-A | Cleaning compositions comprising alkoxylated esteramines | 宝洁公司 | 2020-04-10 | — | — | CN | claimed |
| EP-1790639-B1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS CXCR4-ANTAGONISTS | ONO PHARMACEUTICAL CO (JP) | 2014-03-26 | — | — | EP | claimed |
| US-7951816-B2 | Compound containing basic group and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-05-31 | — | — | US | claimed |
| US-6933272-B1 | Use of non-peptidyl compounds for the treatment of insulin related ailments | HELMERHORST ERIK (AU) | 2005-08-23 | — | — | US | claimed |
| EP-1115422-A4 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | UNIV CURTIN TECH (AU) | 2003-01-29 | — | — | EP | claimed |
| EP-1115422-A1 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | CURTIN UNIVERSITY OF TECHNOLOGY (AU) | 2001-07-18 | — | — | EP | claimed |
| WO-2000016798-A1 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | CURTIN UNIVERSITY OF TECHNOLOGY (AU) | 2000-03-30 | — | — | WO | claimed |
| EP-0760251-A1 | A membrane and method for the separation of aromatic hydrocarbons from a mixture of various aromatic hydrocarbons or from a mixture of such aromatic hydrocarbons and non-aromatic hydrocarbons | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 1997-03-05 | — | — | EP | claimed |
| US-5428059-A | Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient | DAINIPPON INK & CHEMICALS, INC. (JP) | 1995-06-27 | — | — | US | claimed |
| US-5399292-A | Fluoro-substituted phenyl-cyclohexylacetylenes | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | claimed |
| US-5380462-A | Cyclohexyl alkenoate compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-01-10 | — | — | US | claimed |
| US-4906559-A | Light-sensitive silver halide photographic material | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-03-06 | — | — | US | claimed |
| US-4895793-A | 1,1'SPIROBISINDANE COMPOUNDS AS DYE STABILIZERS; ANTISOILANTS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-01-23 | — | — | US | claimed |
| US-4868101-A | SPIROBIBENZOFURANS AS DYE STABILIZERS DISCOLORATION INHIBITIONS; COLOR PRESERVATION | FUJI PHOTO FILM CO., LTD. (JP) | 1989-09-19 | — | — | US | claimed |
| EP-0024960-B1 | SUBSTITUTED HETEROCYCLIC PHENOXY AMINES, THEIR PREPARATION METHOD AND THEIR USE AS LOCAL ANAESTHETICS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1984-12-12 | — | — | EP | claimed |
| EP-0024960-A2 | Substituted heterocyclic phenoxy amines, their preparation method and their use as local anaesthetics | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-03-11 | — | — | EP | claimed |
| CN-115724750-B | Spirofluorene derivative and application thereof | 北京八亿时空液晶科技股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-3932400-A | CARDIOVASCULAR DISORDERS, ANTIARRHYTHMIA AGENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-13 | — | — | US | disclosed |