Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240327 | 0.75 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL3082076 | 0.71 | TSHR (0.32) | TSHRALDH1A1 | |
| SCHEMBL28274266 | 0.70 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL3482446 | 0.70 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL3482111 | 0.68 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL30697923 | 0.67 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL27833358 | 0.67 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL28935156 | 0.67 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL6902592 | 0.65 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL546952 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762574-B | Benzoxapi 3K inhibitor compounds and methods of use | HOFFMAN-LA ROCHE LTD. (CH) | 2015-12-02 | — | — | CN | disclosed |
| CN-104987345-A | BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE | 2015-10-21 | — | — | CN | disclosed |
| CN-101027302-B | Pyrrolo-pyridine kinase modulators | SGX PHARMACEUTICALS INC | 2011-05-11 | — | — | CN | disclosed |
| CN-101679436-A | Fused ring heterocycle kinase modulators | SGX PHARMACEUTICALS INC | 2010-03-24 | — | — | CN | disclosed |
| CN-101389626-A | Fused ring heterocyclic kinase modulators | SGX PHARMACEUTICALS INC (US) | 2009-03-18 | — | — | CN | disclosed |
| CN-101027302-A | Pyrrolo-pyridine kinase modulators | SGX PHARMACEUTICALS INC (US) | 2007-08-29 | — | — | CN | disclosed |