SCHEMBL27699481

SCHEMBL27699481

CC(Br)c1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840248 0.81
SCHEMBL23667845 0.80
SCHEMBL557653 0.80
SCHEMBL2033997 0.77 ADAM17 (0.39)
SCHEMBL16406105 0.77 ADAM17 (0.39)
SCHEMBL9990775 0.77
SCHEMBL3342146 0.76
SCHEMBL19267359 0.76
SCHEMBL21037832 0.76 ALDH1A1 (0.39)
SCHEMBL22768499 0.76 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264193-A Strong coordination PNN tridentate chiral ligand based on inversion effect and application thereof in free radical asymmetric functionalization and related reaction 武汉大学 2025-01-07 CN disclosed
CN-105517440-A Fungicidal 3- { phenyl [ (heterocyclylmethoxy) imino ] methyl } -oxadiazolone derivatives BAYER CROPSCIENCE AG 2016-04-20 CN disclosed
CN-102858767-B As the aminopyrimidine of SYK inhibitor MERCK SHARP & DOHME CORP. (US) 2015-08-19 CN disclosed
CN-104755476-A Method for producing compound SUMITOMO CHEMICAL CO 2015-07-01 CN disclosed
CN-104744446-A Hetero-aromatic compound and application thereof in medicine GUANGDONG HEC PHARMACEUTICAL 2015-07-01 CN disclosed
CN-104619698-A Pyrrolidine derivatives and their use as complement pathway modulators NOVARTIS AG 2015-05-13 CN disclosed
CN-104583218-A Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation BRISTOL MYERS SQUIBB CO 2015-04-29 CN disclosed
CN-104478869-A Oxazolidinone compound and application thereof to drugs GUANGDONG HEC PHARMACEUTICAL 2015-04-01 CN disclosed
CN-101977503-B Fungicide hydroximoyl-tetrazole derivatives BAYER CROPSCIENCE AG 2014-11-19 CN disclosed
CN-104039769-A Fungicidal 3-[(1,3-thiazol-4-ylmethoxyimino)(phenyl)methyl]-2-substituted-1,2,4-oxadiazol-5(2h)-one Derivatives BAYER IP GMBH 2014-09-10 CN disclosed
CN-103649079-A Hepatitis C inhibitor and application thereof ABBVIE INC 2014-03-19 CN disclosed
CN-101163693-B Antibacterial piperidine derivatives ASTRAZENECA AB 2013-03-06 CN disclosed
CN-102906092-A Certain triazolopyridine compounds and triazolopyrazine compounds, compositions thereof and methods of use thereof HUTCHISON MEDIPHARMA LTD 2013-01-30 CN disclosed
CN-101842357-A Substituted pyrazole derivatives TAKEDA PHARMACEUTICAL 2010-09-22 CN disclosed
CN-101163693-A Antibacterial piperidine derivatives ASTRAZENECA AB (SE) 2008-04-16 CN disclosed