Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27813823 | 0.88 | HRH3 (0.60) | HRH3HDAC4KCNH2CYP3A4NAMPT | |
| SCHEMBL451176 | 0.87 | HRH3 (0.59) | HRH3HDAC4KCNH2CYP3A4NAMPT | |
| SCHEMBL451175 | 0.87 | HRH3 (0.59) | HRH3HDAC4KCNH2CYP3A4NAMPT | |
| SCHEMBL15314478 | 0.87 | HRH3 (0.59) | HRH3HDAC4KCNH2CYP3A4NAMPT | |
| SCHEMBL12128175 | 0.87 | HRH3 (0.59) | HRH3HDAC4KCNH2CYP3A4NAMPT | |
| SCHEMBL23550031 | 0.85 | HRH3 (0.58) | HRH3HDAC4KCNH2CYP3A4NAMPT | |
| SCHEMBL18529756 | 0.85 | HRH3 (0.44) | HRH3KCNH2CYP3A4NAMPTFFAR1 | |
| SCHEMBL12128172 | 0.82 | HRH3 (0.55) | HRH3HDAC4KCNH2CYP3A4NAMPT | |
| SCHEMBL451266 | 0.82 | HRH3 (0.55) | HRH3HDAC4KCNH2CYP3A4NAMPT | |
| SCHEMBL15314513 | 0.82 | HRH3 (0.55) | HRH3HDAC4KCNH2CYP3A4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160285-A | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as vr1 receptor antagonists | PFIZER (US) | 2008-04-09 | — | — | CN | disclosed |