Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720126 | 0.93 | BRD4 (0.44) | BRD4TLR8TLR7PTGDR2ALDH1A1 | |
| SCHEMBL27699596 | 0.92 | BRD4 (0.46) | BRD4TLR8TLR7ALDH1A1SMN1; SMN2 | |
| SCHEMBL5514894 | 0.88 | BRD4 (0.48) | BRD4TLR8TLR7PTGDR2ALDH1A1 | |
| SCHEMBL28772256 | 0.88 | BRD4 (0.43) | BRD4TLR8TLR7PTGDR2ALDH1A1 | |
| SCHEMBL5511392 | 0.87 | BRD4 (0.50) | BRD4TLR8TLR7PTGDR2ALDH1A1 | |
| SCHEMBL27751343 | 0.87 | BRD4 (0.44) | BRD4TLR8TLR7ALDH1A1SMN1; SMN2 | |
| SCHEMBL27772050 | 0.85 | BRD4 (0.44) | BRD4TLR8TLR7ALDH1A1SMN1; SMN2 | |
| SCHEMBL27720121 | 0.85 | ALDH1A1 (0.43) | BRD4TLR8TLR7ALDH1A1SMN1; SMN2 | |
| SCHEMBL27772187 | 0.84 | BRD4 (0.43) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL27751366 | 0.83 | BRD4 (0.43) | BRD4TLR8TLR7ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146770-A | 2-phenyl indoles as prostaglandin D2 receptor antagonists | AVENTIS PHARMA INC (US) | 2008-03-19 | — | — | CN | disclosed |