Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28772256 | 0.96 | BRD4 (0.43) | BRD4ALDH1A1L3MBTL1LMNATLR8 | |
| SCHEMBL27720121 | 0.93 | ALDH1A1 (0.43) | BRD4ALDH1A1L3MBTL1LMNATLR8 | |
| SCHEMBL27720126 | 0.92 | BRD4 (0.44) | BRD4ALDH1A1L3MBTL1LMNATLR8 | |
| SCHEMBL27699545 | 0.92 | BRD4 (0.47) | BRD4ALDH1A1L3MBTL1LMNATLR8 | |
| SCHEMBL27772021 | 0.90 | TLR8 (0.42) | BRD4ALDH1A1LMNATLR8TLR7 | |
| SCHEMBL27720087 | 0.90 | BRD4 (0.46) | BRD4LMNATLR8TLR7MEN1 | |
| SCHEMBL27751343 | 0.90 | BRD4 (0.44) | BRD4ALDH1A1L3MBTL1LMNATLR8 | |
| SCHEMBL27772050 | 0.90 | BRD4 (0.44) | BRD4ALDH1A1L3MBTL1LMNATLR8 | |
| SCHEMBL13774339 | 0.89 | BRD4 (0.48) | BRD4ALDH1A1L3MBTL1LMNATLR8 | |
| SCHEMBL27772187 | 0.88 | BRD4 (0.43) | BRD4ALDH1A1L3MBTL1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146770-A | 2-phenyl indoles as prostaglandin D2 receptor antagonists | AVENTIS PHARMA INC (US) | 2008-03-19 | — | — | CN | claimed |
| CN-101495449-A | 2-phenyl-indoles as prostaglandin D2 receptor antagonists | SANOFI AVENTIS (FR) | 2009-07-29 | — | — | CN | disclosed |
| CN-101146770-A | 2-phenyl indoles as prostaglandin D2 receptor antagonists | AVENTIS PHARMA INC (US) | 2008-03-19 | — | — | CN | disclosed |