Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14899045 | 0.83 | AKR1C1 (0.48) | OPRM1SLC6A4ALDH1A1KMT2A | |
| SCHEMBL9378568 | 0.81 | OPRM1 (0.49) | OPRM1OPRD1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL22479057 | 0.81 | OPRM1 (0.52) | OPRM1OPRD1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL27742157 | 0.75 | AKR1C1 (0.42) | OPRM1OPRD1SLC6A4OPRK1ALDH1A1 | |
| SCHEMBL24691526 | 0.75 | OPRM1 (0.46) | OPRM1OPRD1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL9384128 | 0.74 | OPRM1 (0.48) | OPRM1OPRD1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL16015556 | 0.74 | OPRM1 (0.43) | OPRM1OPRD1SLC6A4OPRK1ALDH1A1 | |
| SCHEMBL17215183 | 0.73 | AKR1C1 (0.40) | OPRM1OPRD1SLC6A4OPRK1ALDH1A1 | |
| SCHEMBL3046108 | 0.73 | OPRM1 (0.65) | OPRM1OPRD1SLC22A1SLC6A4ADRA1A | |
| SCHEMBL28765681 | 0.73 | OPRM1 (0.65) | OPRM1OPRD1SLC22A1SLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101027044-A | Oral dosage form safeguarded against abuse | GRUENENTHAL GMBH (DE) | 2007-08-29 | — | — | CN | disclosed |