Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699735 | 0.98 | ALOX5 (0.46) | ALOX5KCNH2GRM2TUBBADORA2A | |
| SCHEMBL27699749 | 0.80 | ALOX5 (0.49) | ALOX5KCNH2GRM2TUBBADORA2A | |
| SCHEMBL27720323 | 0.79 | ALOX5 (0.55) | ALOX5KCNH2GRM2TUBB | |
| SCHEMBL27699684 | 0.78 | ALOX5 (0.56) | ALOX5KCNH2GRM2TUBB | |
| SCHEMBL4080162 | 0.78 | ALOX5 (0.60) | ALOX5KCNH2GRM2TUBB | |
| SCHEMBL27720330 | 0.78 | ALOX5 (0.55) | ALOX5KCNH2GRM2TUBB | |
| SCHEMBL27720333 | 0.76 | ALOX5 (0.50) | ALOX5GRM2TUBBMAOB | |
| SCHEMBL4076155 | 0.76 | ALOX5 (0.60) | ALOX5KCNH2GRM2TUBB | |
| SCHEMBL4075975 | 0.70 | ALOX5 (0.53) | ALOX5MAOB | |
| SCHEMBL28768571 | 0.70 | ALOX5 (0.47) | ALOX5GRM2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146802-A | Thiadiazole-substituted coumarin derivatives and their use as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA LTD (CA) | 2008-03-19 | — | — | CN | claimed |