Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | SORD | Q00796 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720330 | 0.88 | ALOX5 (0.55) | ALOX5ALDH1A1HPGDTUBBCA12 | |
| SCHEMBL27699684 | 0.87 | ALOX5 (0.56) | ALOX5ALDH1A1HPGDTUBBCA12 | |
| SCHEMBL27720323 | 0.84 | ALOX5 (0.55) | ALOX5ALDH1A1HPGDTUBBCA12 | |
| SCHEMBL27699850 | 0.83 | ALOX5 (0.46) | ALOX5ALDH1A1HPGDUSP2MAOB | |
| SCHEMBL28768571 | 0.80 | ALOX5 (0.47) | ALOX5ALDH1A1HPGDUSP2MAOB | |
| SCHEMBL27699749 | 0.80 | ALOX5 (0.49) | ALOX5ALDH1A1HPGDTUBBCA12 | |
| SCHEMBL757238 | 0.80 | GRM2 (0.47) | ALOX5GRM2 | |
| SCHEMBL4088749 | 0.80 | ALOX5 (0.72) | ALOX5ALDH1A1HPGDUSP2TUBB | |
| SCHEMBL27699690 | 0.76 | ALOX5 (0.46) | ALOX5TUBBMAOBGRM2 | |
| SCHEMBL27699735 | 0.76 | ALOX5 (0.46) | ALOX5ALDH1A1HPGDTUBBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146802-A | Thiadiazole-substituted coumarin derivatives and their use as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA LTD (CA) | 2008-03-19 | — | — | CN | claimed |