Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453576 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TDP1LMNAGAAHTT | |
| SCHEMBL2211964 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TDP1LMNAGAAHTT | |
| SCHEMBL24749612 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNAGAAHTT | |
| SCHEMBL30768290 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNAGAAHTT | |
| Hydrochloric Acid SCHEMBL15486437 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAGAAHTT | |
| SCHEMBL20328418 | 0.75 | TDP1 (0.66) | ALDH1A1TDP1LMNAHTTTUBB4A | |
| SCHEMBL29351649 | 0.75 | TDP1 (0.66) | ALDH1A1TDP1LMNAHTTTUBB4A | |
| SCHEMBL29650091 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL20328412 | 0.75 | TDP1 (0.66) | ALDH1A1TDP1LMNAHTTTUBB4A | |
| SCHEMBL397931 | 0.75 | TDP1 (0.66) | ALDH1A1TDP1LMNAHTTTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214409-B | The synthesis of tsiklomitsin and analogue thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-21 | — | — | CN | claimed |
| CN-105452226-A | Tetrahydro-and dihydro-isoquinoline PRMT5 inhibitors and uses thereof | EPIZYME INC | 2016-03-30 | — | — | CN | disclosed |
| CN-101346468-B | amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-30 | — | — | CN | disclosed |
| CN-105339351-A | Arginine methyltransferase inhibitors and uses thereof | EPIZYME INC | 2016-02-17 | — | — | CN | disclosed |
| CN-105228997-A | Carm1 inhibitors and uses thereof | EPIZYME INC | 2016-01-06 | — | — | CN | disclosed |
| CN-105189462-A | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS INC | 2015-12-23 | — | — | CN | disclosed |
| CN-105131067-A | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | RXI PHARMACEUTICALS CORP | 2015-12-09 | — | — | CN | disclosed |
| CN-103214409-B | The synthesis of tsiklomitsin and analogue thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-21 | — | — | CN | disclosed |
| CN-102164987-B | Catalyst and process for synthesizing polymers | NOVOMER INC | 2015-07-08 | — | — | CN | disclosed |
| CN-104350055-A | Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof | AGENCY SCIENCE TECH & RES (SG) | 2015-02-11 | — | — | CN | disclosed |
| CN-104245794-A | Alpha-aminoamidine polymers and their use | MASSACHUSETTS INST TECHNOLOGY | 2014-12-24 | — | — | CN | disclosed |
| CN-102209701-B | Isoprenyl compounds and methods thereof | SIGNUM BIOSCIENCES, INC. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-103380113-A | Amine-containing transfection reagents and methods of making and using same | LIFE TECHNOLOGIES CORP | 2013-10-30 | — | — | CN | disclosed |
| CN-103224474-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-31 | — | — | CN | disclosed |
| CN-103214409-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-24 | — | — | CN | disclosed |
| CN-101027279-B | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-03-27 | — | — | CN | disclosed |
| CN-102164987-A | Catalyst and process for synthesizing polymers | NOVOMER INC | 2011-08-24 | — | — | CN | disclosed |
| CN-101346468-A | Amine-containing lipids and uses thereof | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-01-14 | — | — | CN | disclosed |
| CN-101027279-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE (US) | 2007-08-29 | — | — | CN | disclosed |