Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | BRAF | P15056 | 14/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | CSF1R | P07333 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941843 | 0.94 | BRAF (0.77) | LMNABRAFGAACSF1RKIT | |
| SCHEMBL12978269 | 0.89 | LMNA (1.00) | LMNAGAAALDH1A1 | |
| SCHEMBL3934629 | 0.88 | LMNA (0.77) | LMNABRAFGAACSF1RALDH1A1 | |
| SCHEMBL3937838 | 0.88 | BRAF (0.76) | LMNABRAFGAACSF1RKIT | |
| SCHEMBL3936918 | 0.87 | BRAF (1.00) | BRAFCSF1R | |
| SCHEMBL3937724 | 0.87 | CSF1R (0.83) | BRAFCSF1RKITKDRMAPK14 | |
| SCHEMBL13947089 | 0.86 | LMNA (0.81) | LMNABRAFGAACSF1RALDH1A1 | |
| SCHEMBL3942646 | 0.85 | BRAF (0.83) | BRAFCSF1RALDH1A1 | |
| SCHEMBL3933426 | 0.85 | BRAF (0.84) | BRAFCSF1RALDH1A1 | |
| SCHEMBL3932583 | 0.85 | CSF1R (0.79) | LMNABRAFGAACSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |