Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720607 | 0.84 | KMT2A (0.58) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL27699748 | 0.84 | KMT2A (0.54) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL19150684 | 0.83 | NPC1 (0.44) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL19150685 | 0.83 | NPC1 (0.44) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL19149722 | 0.82 | KCNQ3 (0.54) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL402139 | 0.81 | MAPT (0.77) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL27699783 | 0.79 | HDAC1 (0.51) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL2063757 | 0.79 | KMT2A (0.60) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL3529391 | 0.78 | KMT2A (0.62) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL4067681 | 0.78 | LMNA (0.49) | KMT2ARAB9AMEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |