Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727523 | 0.84 | GAA (0.46) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL27699748 | 0.84 | KMT2A (0.54) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL27699809 | 0.84 | KMT2A (0.54) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL11718206 | 0.82 | POLB (0.46) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL2063757 | 0.81 | KMT2A (0.60) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL6396133 | 0.81 | KMT2A (0.85) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL30449796 | 0.80 | POLB (0.56) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL3455657 | 0.80 | POLB (0.56) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL27699805 | 0.79 | MAPT (0.58) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL25232479 | 0.78 | KMT2A (0.47) | KMT2APOLBNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |