Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 16/20 | 0.53 |
| ▸ | TTR | P02766 | 11/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179851 | 0.80 | RBP4 (0.59) | RBP4TTRKDM4EUSP2HPGD | |
| SCHEMBL5216228 | 0.79 | RBP4 (0.57) | RBP4TTRKDM4EUSP2HPGD | |
| SCHEMBL28764749 | 0.78 | RBP4 (0.60) | RBP4TTRPPARGKDM4EUSP2 | |
| SCHEMBL3113600 | 0.77 | KMT2A (0.60) | RBP4KDM4EUSP2HPGDNPSR1 | |
| SCHEMBL27680981 | 0.75 | KDM4E (0.60) | RBP4TTRKDM4EUSP2HPGD | |
| SCHEMBL13494044 | 0.74 | KDM4E (0.81) | RBP4TTRKDM4EUSP2HPGD | |
| SCHEMBL31426975 | 0.74 | RBP4 (0.56) | RBP4TTRPPARGKDM4EUSP2 | |
| SCHEMBL27680972 | 0.73 | RBP4 (0.54) | RBP4TTRKDM4EUSP2HPGD | |
| SCHEMBL6396185 | 0.73 | RBP4 (0.69) | RBP4TTRPPARGKDM4EUSP2 | |
| SCHEMBL27700146 | 0.72 | KMT2A (0.55) | RBP4KDM4EUSP2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023063-A | Azine-carboxamides as anti-cancer agents | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | disclosed |