Tryptophan

SCHEMBL27700398

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Tryptophan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	19/20	0.46

▸	CCKBR	P32239	1/20	0.45

▸	GCGR	P47871	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Tryptophan SCHEMBL27849549	0.96	GLP1R (0.46)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL27531779	0.96	GLP1R (0.49)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL26967547	0.96	GLP1R (0.49)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL27331432	0.95	GLP1R (0.45)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL27505901	0.94	GLP1R (0.45)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL27700472	0.94	GLP1R (0.45)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL27501630	0.93	IL23R (0.45)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL27448344	0.93	GLP1R (0.44)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL27645885	0.93	GLP1R (0.44)	GLP1RCCKBRGCGR
Tryptophan SCHEMBL27546659	0.91	KEAP1 (0.41)	GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-101035440-A	High protein bean cake	RENESSEN LLC (US)	2007-09-12	—	—	CN	disclosed