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Tryptophan

Tryptophan

SCHEMBL27849549

CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Tryptophan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.46
▸ CCKBR P32239 1/20 0.45
▸ GCGR P47871 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL27531779 0.96 GLP1R (0.49) GLP1RCCKBRGCGR
Tryptophan SCHEMBL27700398 0.96 GLP1R (0.46) GLP1RCCKBRGCGR
Tryptophan SCHEMBL26967547 0.96 GLP1R (0.49) GLP1RCCKBRGCGR
Tryptophan SCHEMBL27331432 0.91 GLP1R (0.45) GLP1RCCKBRGCGR
Tryptophan SCHEMBL27527055 0.91 GLP1R (0.45) GLP1RCCKBRGCGR
Tryptophan SCHEMBL27333689 0.91 GLP1R (0.46) GLP1RCCKBRGCGR
Tryptophan SCHEMBL27568514 0.91 GLP1R (0.43) GLP1RCCKBRGCGR
Tyrosine SCHEMBL27636887 0.90 GLP1R (0.40) GLP1RCCKBRGCGR
Tryptophan SCHEMBL27434560 0.89 GLP1R (0.49) GLP1RCCKBRGCGR
Cystine SCHEMBL27644422 0.89 GLP1R (0.41) GLP1RCCKBRGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102440989-B Detection method of compound amino acid injection SICHUAN KELUN PHARM RES CO LTD 2014-04-02 — — CN disclosed
CN-102440989-A Compound amino acid injection and preparation method and detection method thereof KELUN PHARMACEUTICAL 2012-05-09 — — CN disclosed
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