Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083547 | 0.82 | MAPK14 (0.61) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL14559811 | 0.76 | CYP2C9 (0.61) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL5383885 | 0.76 | GPR84 (0.51) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL8707313 | 0.75 | TPSAB1 (0.61) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL8707900 | 0.75 | MAPK14 (0.60) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL10720113 | 0.74 | CYP2C9 (0.81) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL7234134 | 0.74 | CYP2C9 (1.00) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL3463671 | 0.74 | CYP2C9 (1.00) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL1063927 | 0.74 | CYP2C9 (0.61) | CYP2C9CYP2C19MAPK14HTR2BGRIN2D | |
| SCHEMBL8708970 | 0.73 | CYP2C9 (0.60) | MEN1KMT2ACYP2C9CYP2C19MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101102787-A | Synthetic hyperglycosylated, and hyperglycosylated protease-resistant polypeptide variants, oral formulations and methods of using the same | ALIOS BIOPHARMA INC (US) | 2008-01-09 | — | — | CN | disclosed |