Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770071 | 1.00 | TRPV1 (0.40) | TRPV1PPARGPPARAFNTAFNTB | |
| SCHEMBL2241999 | 0.81 | ESR1 (0.41) | MAPTLMNACYP1A2HSD17B10KMT2A | |
| SCHEMBL2242003 | 0.81 | ESR1 (0.41) | MAPTLMNACYP1A2HSD17B10KMT2A | |
| SCHEMBL12345347 | 0.81 | ESR1 (0.41) | MAPTLMNACYP1A2HSD17B10KMT2A | |
| SCHEMBL6236596 | 0.79 | TRPV1 (0.43) | TRPV1FNTAFNTBCYP3A4MAPT | |
| SCHEMBL2768432 | 0.78 | FNTA (0.36) | TRPV1PPARGPPARAFNTAFNTB | |
| SCHEMBL2768625 | 0.78 | FNTA (0.36) | TRPV1PPARGPPARAFNTAFNTB | |
| SCHEMBL3125298 | 0.77 | MAPT (0.53) | TRPV1CYP3A4MAPTLMNACYP1A2 | |
| SCHEMBL7712236 | 0.75 | ESR1 (0.42) | LMNAESR1MAPK1SMN1; SMN2 | |
| SCHEMBL9310242 | 0.75 | CES2 (0.50) | LMNAKMT2AATMESR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824952-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-04-28 | — | — | EP | claimed |