SCHEMBL7712236

SCHEMBL7712236

CC(CCN)=C(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.42
CYP19A1 P11511 1/20 0.42
ESR2 Q92731 1/20 0.42
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
ADRA2C P18825 1/20 0.38
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTGS2 P35354 1/20 0.36
CYP2A6 P11509 1/20 0.36
HTR2A P28223 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
F12 P00748 1/20 0.36
F7 P08709 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2222705 0.84 ESR1 (0.43) ESR1CYP19A1ESR2CES2CES1
SCHEMBL9310242 0.82 CES2 (0.50) ESR1CES2CES1LMNAL3MBTL1
SCHEMBL11043479 0.80 PTGS2 (0.42) ESR1CYP19A1ESR2CES2CES1
SCHEMBL10556310 0.78 ALDH1A1 (0.55) MAPK1HTTL3MBTL1SMN1; SMN2
SCHEMBL21462935 0.78 PTGS2 (0.55) ESR1CES2CES1PTGS2
SCHEMBL2239644 0.78 NR4A2 (0.57) ESR1CYP19A1CES2CES1LMNA
SCHEMBL29650929 0.78 ALDH1A1 (0.55) MAPK1HTTL3MBTL1SMN1; SMN2
SCHEMBL2172806 0.76 ESR1 (0.45) ESR1CYP19A1CES2CES1LMNA
SCHEMBL2172813 0.76 ESR1 (0.45) ESR1CYP19A1CES2CES1LMNA
SCHEMBL2767079 0.76 ATM (0.48) ESR1CYP19A1ESR2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109312117-A Rubber composition 盛禧奥欧洲有限责任公司 2019-02-05 CN claimed
CN-107466307-A Polymer blend for tires 盛禧奥欧洲有限责任公司 2017-12-12 CN claimed
CN-107454907-A Functionalized polymer blends for tires 盛禧奥欧洲有限责任公司 2017-12-08 CN claimed
CN-101074515-B Telescopic nonwoven fabric KAO CORP 2011-02-09 CN claimed
CN-1652756-A Matrix type patch containing bronchodilators AHN GOOK PHARMACEUTICAL CO LTD (KR) 2005-08-10 CN claimed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP claimed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO claimed
CN-105026440-B Modified conjugated diene polymer, method for producing same, polymer composition, crosslinked polymer, and tire JSR株式会社 2018-02-16 CN disclosed
CN-103210145-B For increasing composition and the method for the dry strength of paper product Camiro Head Office (FI) 2016-05-25 CN disclosed
CN-103210145-A Composition and process for increasing the dry strength of a paper product KEMIRA OYJ 2013-07-17 CN disclosed
CN-101557929-B Stretchable sheet and process for producing the stretchable sheet KAO CORP 2012-09-05 CN disclosed
CN-101074515-B Telescopic nonwoven fabric KAO CORP 2011-02-09 CN disclosed
CN-101778873-A High solids glyoxalated polyacrylamide BUCKMAN LABOR INC 2010-07-14 CN disclosed
CN-101074515-A Telescopic nonwoven fabric KAO CORP (JP) 2007-11-21 CN disclosed
CN-1253233-C Filter for blood treatment and method for producing the same ASAHI MEDICAL CO (JP) 2006-04-26 CN disclosed
CN-1652756-A Matrix type patch containing bronchodilators AHN GOOK PHARMACEUTICAL CO LTD (KR) 2005-08-10 CN disclosed
CN-1489485-A Filter for blood treatment and method for producing the same ��ҽѧ��ʽ���� 2004-04-14 CN disclosed
US-6361768-B1 POLYMER FORMED BY COPOLYMERIZATION OF ANIONIC MONOMER HAVING CARBOXY-FUNCTIONAL GROUP, NON-QUATERNIZED CATIONIC MONOMER HAVING AMINO-FUNCTIONAL GROUP, NON-IONIC HYDROPHILIC MONOMER, HYDROPHOBIC MONOMER, OPTIONAL CROSSLINKING MONOMER PMD HOLDINGS CORP. 2002-03-26 US disclosed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP disclosed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO disclosed