Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28808801 | 0.98 | TP53 (0.47) | TP53CA1CA2FDPSMAPK1 | |
| Sulfuric Acid SCHEMBL28243103 | 0.91 | TP53 (0.50) | TP53CA1CA2FDPSMAPK1 | |
| Sulfuric Acid SCHEMBL17102699 | 0.87 | TP53 (0.50) | TP53CA1CA2MAPK1TSHR | |
| Sulfuric Acid SCHEMBL4958607 | 0.87 | TP53 (0.50) | TP53CA1CA2MAPK1TSHR | |
| Sulfuric Acid SCHEMBL29270371 | 0.86 | TP53 (0.41) | TP53CA1CA2FDPSMAPK1 | |
| SCHEMBL1293511 | 0.84 | TP53 (0.40) | TP53CA1CA2FDPSMAPK1 | |
| Ammonia Solution, Strong SCHEMBL27730912 | 0.83 | TP53 (0.39) | TP53CA1CA2FDPSMAPK1 | |
| Sulfuric Acid SCHEMBL3343165 | 0.79 | DNM1 (0.52) | TP53CA1CA2FDPSMAPK1 | |
| SCHEMBL715412 | 0.78 | RECQL (0.41) | TP53CA1CA2FDPSMAPK1 | |
| Sulfuric Acid SCHEMBL27729946 | 0.78 | DNM1 (0.41) | TP53CA1CA2FDPSMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103804162-B | Method for preparing high-purity 9-fluorenone from high-purity fluorene | 宝舜科技股份有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-103435463-B | A kind of four phase phase-transfer catalysiss prepare the method for 9-Fluorenone | BAOSHUN TECHNOLOGY CO., LTD. (CN) | 2015-09-02 | — | — | CN | claimed |
| CN-103804162-A | Method for preparing high-purity 9-fluorenone from high-purity fluorene | BAOSHUN TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | claimed |
| CN-103467264-A | Method for preparing 9-fluorenone through using industrial fluorene | BAOSHUN TECHNOLOGY CO LTD | 2013-12-25 | — | — | CN | claimed |
| CN-103435463-A | Method for preparing 9-fluorenone via four-phase transfer catalysis | BAOSHUN TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | claimed |
| CN-103804162-B | Method for preparing high-purity 9-fluorenone from high-purity fluorene | 宝舜科技股份有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-103467264-B | A kind of method being prepared 9-Fluorenone by Industrial fluorene | BAOSHUN TECHNOLOGY CO., LTD. (CN) | 2016-01-27 | — | — | CN | disclosed |
| CN-103435463-B | A kind of four phase phase-transfer catalysiss prepare the method for 9-Fluorenone | BAOSHUN TECHNOLOGY CO., LTD. (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103787858-B | Method for preparing 9-fluorenone through fluorene | BAOSHUN TECHNOLOGY CO LTD | 2015-07-01 | — | — | CN | disclosed |
| CN-103435456-B | Preparation method for 9-fluorenone | BAOSHUN TECHNOLOGY CO LTD | 2015-06-10 | — | — | CN | disclosed |
| CN-103804162-A | Method for preparing high-purity 9-fluorenone from high-purity fluorene | BAOSHUN TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | disclosed |
| CN-103787858-A | Method for preparing 9-fluorenone through fluorene | BAOSHUN TECHNOLOGY CO LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-103467264-A | Method for preparing 9-fluorenone through using industrial fluorene | BAOSHUN TECHNOLOGY CO LTD | 2013-12-25 | — | — | CN | disclosed |
| CN-103435463-A | Method for preparing 9-fluorenone via four-phase transfer catalysis | BAOSHUN TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | disclosed |
| CN-103435456-A | Preparation method for 9-fluorenone | BAOSHUN TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | disclosed |
| CN-100591407-C | Method for separating hydrogen chloride and phosgene | BASF AG | 2010-02-24 | — | — | CN | disclosed |
| CN-101018596-A | Method for separating hydrogen chloride and phosgene | BASF AG (DE) | 2007-08-15 | — | — | CN | disclosed |