Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28102813 | 0.78 | EGFR (0.37) | AREGFR | |
| SCHEMBL29496262 | 0.77 | POLB (0.43) | GPR119MAPTCKS1BSKP1SKP2 | |
| SCHEMBL29376524 | 0.76 | EGFR (0.38) | AREGFR | |
| SCHEMBL29930920 | 0.76 | GPR119 (0.40) | GPR119CYP11B2 | |
| SCHEMBL30838601 | 0.71 | GRIN2B (0.42) | EGFR | |
| SCHEMBL5184141 | 0.71 | BCHE (0.47) | GPR119CKS1BSKP1SKP2 | |
| SCHEMBL27869342 | 0.70 | PIK3CD (0.45) | GPR119CYP11B2CKS1BSKP1SKP2 | |
| SCHEMBL28166086 | 0.69 | DYRK2 (0.35) | GPR119 | |
| SCHEMBL28813437 | 0.68 | KMT2A (0.41) | GPR119 | |
| SCHEMBL15252478 | 0.68 | BCHE (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745295-A | BRM targeting compounds and related methods of use | 普莱鲁德疗法有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-101044123-A | Pyrimidine derivatives condensed with non-aromatic rings | ASTELLAS PHARMA INC (JP) | 2007-09-26 | — | — | CN | disclosed |