Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701280 | 0.81 | — | — | |
| SCHEMBL27701228 | 0.81 | HTR1D (0.33) | HTR1DHTR1B | |
| SCHEMBL1031183 | 0.78 | CHRNB2 (0.41) | HTR1DHTR1BCRBNCHRNB2CHRNA4 | |
| SCHEMBL5005427 | 0.77 | HTR1D (0.55) | HTR1DHTR1BMAPT | |
| SCHEMBL27682141 | 0.77 | HDAC1 (0.34) | PARP10CCR2 | |
| SCHEMBL3816206 | 0.75 | RBP4 (0.39) | HTR1DHTR1BPARP10CCR2 | |
| SCHEMBL27682140 | 0.74 | DDB1 (0.41) | PARP10CRBN | |
| SCHEMBL27682112 | 0.73 | SCN9A (0.31) | — | |
| SCHEMBL23113445 | 0.73 | BACE1 (0.42) | CHRNB2CHRNA4ALDH1A1MAPTGFER | |
| SCHEMBL27682115 | 0.71 | CRBN (0.30) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101035534-A | Amino substituted aryloxybenzylpiperidine derivatives | LUNDBECK & CO AS H (DK) | 2007-09-12 | — | — | CN | disclosed |