Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31470357 | 0.86 | CPB1 (0.57) | ALDH1A1GAATACR1CPB1 | |
| SCHEMBL27701237 | 0.84 | KCNA5 (0.53) | ALDH1A1MEN1KMT2ASGMS2MAPT | |
| SCHEMBL31470310 | 0.81 | KMT2A (0.52) | KMT2AL3MBTL1TACR1CPB1 | |
| SCHEMBL16223895 | 0.80 | EPHX2 (0.45) | BCHEALDH1A1MEN1KMT2AATM | |
| SCHEMBL26115455 | 0.80 | ALDH1A1 (0.44) | BCHEALDH1A1MEN1KMT2AATM | |
| SCHEMBL30645029 | 0.80 | ALDH1A1 (0.44) | BCHEALDH1A1MEN1KMT2AATM | |
| SCHEMBL16223894 | 0.80 | EPHX2 (0.45) | BCHEALDH1A1MEN1KMT2AATM | |
| SCHEMBL26112895 | 0.80 | ALDH1A1 (0.44) | BCHEALDH1A1MEN1KMT2AATM | |
| SCHEMBL31470384 | 0.79 | CARM1 (0.47) | BCHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16224216 | 0.79 | EPHX2 (0.44) | ALDH1A1MEN1KMT2ASGMS2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099648-A1 | PYRAOLO- AND TRIAZOLO-AZINONE COMPOUNDS AND THEIR USES | ASTRAZENECA AB (SE) | 2023-06-08 | — | — | WO | disclosed |