SCHEMBL2770135

SCHEMBL2770135

Cc1ccc(N(c2ccc(C)cc2)C2(Br)C=CC(c3ccccc3)=CC2)cc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21647633 0.90
SCHEMBL2771064 0.86 HSD17B1 (0.32) TSHR
SCHEMBL28696388 0.86 ALDH1A1 (0.34)
SCHEMBL2770517 0.85
SCHEMBL5551882 0.83 CYP2C19 (0.33) CYP2C19
SCHEMBL1255776 0.82 CYP2C19 (0.32) CYP2C19
SCHEMBL1929150 0.82 CYP2C19 (0.32) CYP2C19
SCHEMBL4882786 0.81
SCHEMBL27239134 0.81 CYP2C19 (0.31) CYP2C19
SCHEMBL2770707 0.81 CYP2C19 (0.31) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1965260-B1 Imaging member comprising asymmetric arylamine compounds and processes for making these compounds XEROX CORP (US) 2010-04-21 EP disclosed
EP-1965260-A1 Asymmetric arylamine compounds and processes for making the same Xerox Corporation (US) 2008-09-03 EP disclosed
US-20080206662-A1 Asymmetric arylamine compounds and processes for making the same XEROX CORPORATION (US) 2008-08-28 US disclosed