Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501932 | 0.76 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDEPHX2 | |
| SCHEMBL8504795 | 0.76 | CYSLTR2 (0.53) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL8506161 | 0.75 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDPLA2G2A | |
| SCHEMBL8502032 | 0.74 | HSD17B3 (0.45) | MEN1KMT2AALDH1A1HPGDPLA2G2A | |
| SCHEMBL8504440 | 0.73 | KMT2A (0.50) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5502756 | 0.71 | CTSA (0.53) | — | |
| SCHEMBL468843 | 0.70 | KMT2A (0.51) | MEN1KMT2AALDH1A1HPGDPLA2G2A | |
| SCHEMBL468844 | 0.70 | KMT2A (0.51) | MEN1KMT2AALDH1A1HPGDPLA2G2A | |
| SCHEMBL468841 | 0.70 | KMT2A (0.51) | MEN1KMT2AALDH1A1HPGDPLA2G2A | |
| SCHEMBL468842 | 0.70 | KMT2A (0.51) | MEN1KMT2AALDH1A1HPGDPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101084216-B | Inhibitors for the soluble epoxide hydrolase | UNIV CALIFORNIA | 2011-09-14 | — | — | CN | disclosed |
| CN-101084216-A | Inhibitors for the soluble epoxide hydrolase | UNIV CALIFORNIA (US) | 2007-12-05 | — | — | CN | disclosed |