Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504795 | 0.89 | CYSLTR2 (0.53) | MEN1ALDH1A1HPGDKMT2AACACB | |
| SCHEMBL8504440 | 0.85 | KMT2A (0.50) | MEN1ALDH1A1HPGDKMT2AACACB | |
| SCHEMBL8506161 | 0.79 | MEN1 (0.44) | MEN1ALDH1A1HPGDKMT2ACYSLTR2 | |
| SCHEMBL8502032 | 0.78 | HSD17B3 (0.45) | MEN1ALDH1A1HPGDKMT2APLA2G2A | |
| SCHEMBL11255781 | 0.72 | TSHR (0.47) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8501935 | 0.72 | EPHX2 (0.39) | ALDH1A1HPGDEPHX2LMNARAB9A | |
| SCHEMBL11255780 | 0.71 | P2RY10 (0.52) | EPHX2 | |
| SCHEMBL6571652 | 0.70 | NPC1 (0.51) | HPGDNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9773153 | 0.70 | NPC1 (0.62) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9773152 | 0.70 | NPC1 (0.62) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948820-A | IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |