Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.53 |
| ▸ | ACACB | O00763 | 2/20 | 0.48 |
| ▸ | ACACA | Q13085 | 2/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504440 | 0.91 | KMT2A (0.50) | CYSLTR2CYSLTR1ACACBACACAMEN1 | |
| SCHEMBL8501932 | 0.89 | MEN1 (0.44) | CYSLTR2CYSLTR1ACACBACACAMEN1 | |
| SCHEMBL8506161 | 0.81 | MEN1 (0.44) | CYSLTR2CYSLTR1MEN1ALDH1A1HPGD | |
| SCHEMBL8502032 | 0.80 | HSD17B3 (0.45) | THRATHRBMEN1ALDH1A1HPGD | |
| SCHEMBL7686743 | 0.76 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1ACACBACACASMPD1 | |
| SCHEMBL27701466 | 0.76 | MEN1 (0.44) | MEN1ALDH1A1HPGDKMT2ATSHR | |
| SCHEMBL6569106 | 0.75 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1SMPD1THRATHRB | |
| SCHEMBL8504797 | 0.73 | CACNA1B (0.51) | SMPD1THRATHRBPLA2G4BCYP2D6 | |
| SCHEMBL11603858 | 0.72 | ALOX5 (0.61) | CYSLTR2CYSLTR1SMPD1THRATHRB | |
| SCHEMBL9773152 | 0.72 | NPC1 (0.62) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948820-A | IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |