Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 9/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17338702 | 0.79 | APLNR (0.39) | CA1CA2CA7MEN1GAA | |
| SCHEMBL6183615 | 0.78 | CYP2D6 (0.36) | CA1CA2CA7MEN1GAA | |
| SCHEMBL2580333 | 0.77 | SLC1A1 (0.44) | MEN1GAAKMT2AAPLNR | |
| SCHEMBL4954829 | 0.77 | SLC1A1 (0.44) | MEN1GAAKMT2AAPLNR | |
| SCHEMBL11016322 | 0.77 | SLC1A1 (0.44) | MEN1GAAKMT2AAPLNR | |
| SCHEMBL29975263 | 0.77 | MEN1 (0.54) | CA1CA2CA7MEN1GAA | |
| SCHEMBL20075455 | 0.77 | MEN1 (0.54) | CA1CA2CA7MEN1GAA | |
| SCHEMBL7530366 | 0.77 | MEN1 (0.54) | CA1CA2CA7MEN1GAA | |
| SCHEMBL19974086 | 0.76 | MEN1 (0.36) | CA1CA2CA7MEN1GAA | |
| SCHEMBL5672978 | 0.76 | TDP1 (0.40) | CA1CA2CA7MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482680-C | excitatory amino acid prodrugs | LILLY CO ELI (US) | 2009-04-29 | — | — | CN | disclosed |
| CN-101084236-A | excitatory amino acid prodrugs | LILLY CO ELI (US) | 2007-12-05 | — | — | CN | disclosed |