SCHEMBL17338702

SCHEMBL17338702

CC(C)(C)OC(=O)NC(=O)CCN

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 6/20 0.37
CA2 P00918 5/20 0.37
CA7 P43166 3/20 0.37
CTSK P43235 2/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
CA12 O43570 3/20 0.35
CA14 Q9ULX7 3/20 0.35
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
ACE P12821 1/20 0.34
DGAT1 O75907 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5672978 0.89 TDP1 (0.40) APLNRTDP1CA1CA2CA7
SCHEMBL22018439 0.83 TDP1 (0.44) APLNRTDP1CA1CA2CA7
SCHEMBL10087239 0.82 APLNR (0.53) APLNRTDP1CA1CA2CA7
SCHEMBL20288786 0.82 CA1 (0.43) APLNRTDP1CA1CA2CA7
SCHEMBL28755464 0.81 MAOA (0.45) APLNRTDP1CA1CA2CA7
SCHEMBL9424991 0.80 APLNR (0.39) APLNRTDP1CA1CA2CA7
SCHEMBL1261150 0.80 CYP2D6 (0.40) APLNRTDP1CA1CA2CA7
SCHEMBL1262568 0.80 PHF8 (0.42) APLNRTDP1CA1CA2CA7
SCHEMBL1025398 0.79 TDP1 (0.50) TDP1CA1CA2MAOAMAOB
SCHEMBL27701546 0.79 CA1 (0.38) APLNRTDP1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456192-B Compounds, polymers, ligand functionalized substrates and uses 3M创新产权公司 2024-10-22 CN disclosed
CN-113474082-B Ligand Linker Substrate 科雷托公司 2024-05-28 CN disclosed
CN-114452961-B Use of ligand-functionalized substrates for purifying target biomolecules 科雷托公司 2024-05-28 CN disclosed
WO-2015190700-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING SEPSIS 성균관대학교산학협력단 2015-12-17 WO disclosed