Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701631 | 0.89 | HDAC1 (0.42) | HDAC1AGTR1AGTR2 | |
| SCHEMBL27722216 | 0.88 | HDAC1 (0.41) | HDAC1AGTR1AGTR2 | |
| SCHEMBL27722197 | 0.88 | HDAC1 (0.41) | HDAC1AGTR1AGTR2 | |
| SCHEMBL27701827 | 0.88 | HDAC1 (0.41) | HDAC1AGTR1AGTR2 | |
| SCHEMBL27722222 | 0.86 | ALDH1A1 (0.39) | ALDH1A1LMNAPKMRAB9AKDM4E | |
| SCHEMBL27701800 | 0.84 | HDAC1 (0.42) | HDAC1 | |
| SCHEMBL27722204 | 0.83 | HDAC1 (0.44) | HDAC1 | |
| SCHEMBL27722391 | 0.83 | GAA (0.40) | HDAC1ALDH1A1LMNAPKMRAB9A | |
| SCHEMBL27701632 | 0.81 | HDAC1 (0.35) | HDAC1 | |
| SCHEMBL27701649 | 0.81 | HDAC1 (0.37) | HDAC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |