SCHEMBL27701800

SCHEMBL27701800

CCCCc1nc2cc(C)cc(C)n2c1NCC(=O)NO

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 19/20 0.42
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27722262 0.86 KMT2A (0.40) HDAC1KMT2A
SCHEMBL27701637 0.84 HDAC1 (0.42) HDAC1
SCHEMBL27722218 0.83 KMT2A (0.38) HDAC1KMT2A
SCHEMBL27722204 0.79 HDAC1 (0.44) HDAC1
SCHEMBL27722224 0.78 KMT2A (0.39) HDAC1KMT2A
SCHEMBL27701644 0.77 HDAC1 (0.57) HDAC1
SCHEMBL27701631 0.77 HDAC1 (0.42) HDAC1
SCHEMBL27722197 0.76 HDAC1 (0.41) HDAC1
SCHEMBL27722216 0.76 HDAC1 (0.41) HDAC1
SCHEMBL27701827 0.76 HDAC1 (0.41) HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101163703-B Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors NOVARTIS AG 2010-12-15 CN disclosed
CN-101163703-A Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors NOVARTIS AG (CH) 2008-04-16 CN disclosed