Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701722 | 0.89 | HDAC1 (0.41) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL27701655 | 0.89 | GAA (0.41) | HDAC1KDM4EALDH1A1LMNAGLA | |
| SCHEMBL27722200 | 0.88 | HDAC1 (0.41) | HDAC1 | |
| SCHEMBL27722220 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL27701658 | 0.81 | ATP4A (0.48) | — | |
| SCHEMBL27722212 | 0.81 | PLAU (0.39) | HDAC1KDM4EALDH1A1LMNAGLA | |
| SCHEMBL27722329 | 0.78 | KDM4E (0.38) | HDAC1KDM4EALDH1A1LMNAGLA | |
| SCHEMBL27701912 | 0.75 | HDAC1 (0.49) | HDAC1 | |
| SCHEMBL27701734 | 0.74 | SMN1; SMN2 (0.41) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL27701644 | 0.74 | HDAC1 (0.57) | HDAC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |