Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701696 | 0.89 | HDAC1 (0.41) | HDAC1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL27722200 | 0.88 | HDAC1 (0.41) | HDAC1 | |
| SCHEMBL27701734 | 0.86 | SMN1; SMN2 (0.41) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27701698 | 0.82 | HDAC8 (0.45) | HSD17B10KDM4EALDH1A1HPGDCASP7 | |
| SCHEMBL27701658 | 0.81 | ATP4A (0.48) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27701655 | 0.77 | GAA (0.41) | HDAC1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL27701644 | 0.76 | HDAC1 (0.57) | HDAC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27701649 | 0.76 | HDAC1 (0.37) | HDAC1 | |
| SCHEMBL27701637 | 0.74 | HDAC1 (0.42) | HDAC1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL27722220 | 0.73 | KDM4E (0.39) | HSD17B10KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |