Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722223 | 0.88 | GAA (0.49) | KDM4EALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL27701785 | 0.87 | HDAC1 (0.39) | KDM4EALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL27701843 | 0.87 | TRPA1 (0.46) | RAB9AHDAC1GABRA1GABRB2NPC1 | |
| SCHEMBL27701660 | 0.87 | GAA (0.46) | KDM4EALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL27722214 | 0.87 | HDAC1 (0.39) | RAB9AHDAC1NPC1GAAGFER | |
| SCHEMBL27701644 | 0.78 | HDAC1 (0.57) | KDM4EALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL27722199 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL27722263 | 0.77 | HDAC1 (0.35) | HDAC1 | |
| SCHEMBL27722205 | 0.76 | ALDH1A1 (0.36) | KDM4EALDH1A1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL27722224 | 0.76 | KMT2A (0.39) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |