Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722218 | 0.87 | KMT2A (0.38) | KMT2ACREBBPMEP1BKDM4EHDAC1 | |
| SCHEMBL27701800 | 0.86 | HDAC1 (0.42) | KMT2AHDAC1 | |
| SCHEMBL27722222 | 0.82 | ALDH1A1 (0.39) | KMT2AKDM4E | |
| SCHEMBL27722224 | 0.81 | KMT2A (0.39) | KMT2ACREBBPMEP1BHDAC1 | |
| SCHEMBL27701899 | 0.73 | GPR139 (0.33) | MEP1B | |
| SCHEMBL27701908 | 0.73 | GRIN1 (0.33) | MEP1BPDE5AHDAC1 | |
| SCHEMBL27722333 | 0.73 | PKM (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27701782 | 0.72 | NRP1 (0.32) | MEP1BKDM4E | |
| SCHEMBL27722391 | 0.70 | GAA (0.40) | KDM4EHDAC1 | |
| SCHEMBL27722226 | 0.70 | HDAC1 (0.39) | CREBBPKDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |