SCHEMBL27701934

SCHEMBL27701934

O=C(CS)OC(=O)c1ccccc1.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
F2 P00734 1/20 0.50
TDP1 Q9NUW8 4/20 0.47
TSHR P16473 5/20 0.47
KMT2A Q03164 4/20 0.46
MAPK1 P28482 2/20 0.46
HIF1A Q16665 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
ALDH1A1 P00352 4/20 0.44
TP53 P04637 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28201569 0.98 LMNA (0.52) LMNAF2TDP1TSHRKMT2A
SCHEMBL28868136 0.82 LMNA (0.55) LMNAF2TDP1TSHRKMT2A
SCHEMBL20531234 0.82 LMNA (0.55) LMNAF2TDP1TSHRKMT2A
SCHEMBL2611692 0.81 TSHR (0.58) LMNAF2TDP1TSHRKMT2A
SCHEMBL9318015 0.81 LMNA (0.56) LMNAF2TDP1TSHRKMT2A
SCHEMBL4828715 0.81 CES1 (0.42) LMNAF2TDP1TSHRKMT2A
SCHEMBL431406 0.80 LMNA (0.67) LMNAF2TDP1TSHRKMT2A
SCHEMBL2591454 0.80 LMNA (0.67) LMNAF2TDP1TSHRKMT2A
SCHEMBL2762264 0.80 LMNA (0.50) LMNAF2TDP1TSHRKMT2A
SCHEMBL28160533 0.80 LMNA (0.53) LMNAF2TDP1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101824757-B Method for dyeing polyphenylene sulfide fiber or fabric UNIV SICHUAN 2011-09-28 CN claimed
CN-101824757-A Method for dyeing polyphenylene sulfide fiber or fabric UNIV SICHUAN 2010-09-08 CN claimed
CN-100482884-C Surface modifier for transfer printing with dispersive cotton fabric dye and its pre-treatment method UNIV SICHUAN (CN) 2009-04-29 CN claimed
CN-101046060-A Surface modifier for transfer printing with dispersive cotton fabric dye and its pre-treatment method UNIV SICHUAN (CN) 2007-10-03 CN claimed
CN-109281197-B Acrylate emulsion modifier for thermal transfer printing of cotton fabric disperse dye and preparation method thereof 辽宁恒星精细化工有限公司 2020-09-25 CN disclosed
CN-110230213-A Using the preparation method of the modified cellulose fibre fabric of disperse dyeing 鲁泰纺织股份有限公司 2019-09-13 CN disclosed
CN-101824757-B Method for dyeing polyphenylene sulfide fiber or fabric UNIV SICHUAN 2011-09-28 CN disclosed
CN-101824757-A Method for dyeing polyphenylene sulfide fiber or fabric UNIV SICHUAN 2010-09-08 CN disclosed
CN-100482884-C Surface modifier for transfer printing with dispersive cotton fabric dye and its pre-treatment method UNIV SICHUAN (CN) 2009-04-29 CN disclosed
CN-101046060-A Surface modifier for transfer printing with dispersive cotton fabric dye and its pre-treatment method UNIV SICHUAN (CN) 2007-10-03 CN disclosed