Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186246 | 0.98 | LMNA (0.52) | LMNAF2TDP1TSHRALDH1A1 | |
| SCHEMBL2762547 | 0.96 | LMNA (0.50) | LMNAF2TDP1TSHRALDH1A1 | |
| SCHEMBL29035467 | 0.91 | ELANE (0.51) | LMNAF2TDP1TSHRALDH1A1 | |
| SCHEMBL29382078 | 0.87 | LOXL2 (0.45) | LMNAF2TDP1TSHRALDH1A1 | |
| SCHEMBL29381825 | 0.84 | LOXL2 (0.47) | LMNAF2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL28414959 | 0.84 | LMNA (0.50) | LMNAF2TDP1TSHRALDH1A1 | |
| SCHEMBL29035397 | 0.84 | SMN1; SMN2 (0.58) | ALDH1A1KMT2AMAPTPARP10SMN1; SMN2 | |
| SCHEMBL28194586 | 0.82 | LMNA (0.44) | LMNAF2TDP1TSHRALDH1A1 | |
| SCHEMBL28868136 | 0.82 | LMNA (0.55) | LMNAF2TDP1TSHRALDH1A1 | |
| SCHEMBL20531234 | 0.82 | LMNA (0.55) | LMNAF2TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2241654-A2 | Surface-treated metal material excelllent in resistance against galvanic corrosion and joined article of dissimilar materials including the surface-treated metal material | Kabushiki Kaisha Kobe Seiko Sho (JP) | 2010-10-20 | — | — | EP | disclosed |