Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 17/20 | 0.75 |
| ▸ | ERCC5 | P28715 | 8/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113290 | 0.88 | FEN1 (0.84) | FEN1ERCC5 | |
| SCHEMBL5104130 | 0.86 | FEN1 (0.59) | FEN1ERCC5 | |
| SCHEMBL20864156 | 0.86 | FEN1 (1.00) | FEN1ERCC5 | |
| SCHEMBL5107730 | 0.85 | FEN1 (0.58) | FEN1ERCC5 | |
| SCHEMBL14208537 | 0.83 | FEN1 (0.60) | FEN1ERCC5 | |
| SCHEMBL20856770 | 0.81 | FEN1 (0.71) | FEN1ERCC5 | |
| SCHEMBL14414470 | 0.80 | FEN1 (0.65) | FEN1ERCC5 | |
| SCHEMBL27724204 | 0.78 | ERCC5 (0.76) | FEN1ERCC5 | |
| SCHEMBL20864213 | 0.77 | ERCC5 (1.00) | FEN1ERCC5 | |
| SCHEMBL14208494 | 0.76 | FEN1 (0.69) | FEN1ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189240-A | Thienopyridinone derivatives as macrophage migration inhibitory factor inhibitors | AVANIR PHARMACEUTICALS (US) | 2008-05-28 | — | — | CN | disclosed |