Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 10/20 | 0.76 |
| ▸ | FEN1 | P39748 | 14/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703558 | 0.89 | ERCC5 (0.83) | ERCC5FEN1 | |
| SCHEMBL5104213 | 0.87 | FEN1 (0.78) | ERCC5FEN1 | |
| SCHEMBL20864081 | 0.86 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20856784 | 0.80 | ERCC5 (0.70) | ERCC5FEN1 | |
| SCHEMBL27836563 | 0.79 | P2RX4 (0.61) | ERCC5FEN1 | |
| SCHEMBL5107972 | 0.78 | FEN1 (0.85) | ERCC5FEN1 | |
| SCHEMBL27703603 | 0.78 | FEN1 (0.75) | ERCC5FEN1 | |
| SCHEMBL20864419 | 0.77 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864169 | 0.77 | FEN1 (0.70) | ERCC5FEN1 | |
| SCHEMBL20864212 | 0.76 | FEN1 (1.00) | ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189240-A | Thienopyridinone derivatives as macrophage migration inhibitory factor inhibitors | AVANIR PHARMACEUTICALS (US) | 2008-05-28 | — | — | CN | disclosed |