Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944391 | 0.83 | FGFR1 (0.57) | KDM4ENPC1L3MBTL1ALDH1A1ATM | |
| SCHEMBL10357737 | 0.81 | CA12 (0.51) | KDM4ENPC1L3MBTL1ALDH1A1ATM | |
| SCHEMBL19911581 | 0.76 | NPC1 (1.00) | KDM4ENPC1L3MBTL1ALDH1A1ATM | |
| SCHEMBL19911612 | 0.76 | NPC1 (0.66) | KDM4ENPC1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9505827 | 0.76 | NPC1 (0.66) | KDM4ENPC1L3MBTL1ALDH1A1ATM | |
| SCHEMBL18167005 | 0.76 | KDM4E (0.66) | KDM4ENPC1L3MBTL1ALDH1A1FGFR1 | |
| SCHEMBL3807006 | 0.76 | NPC1 (0.66) | KDM4ENPC1L3MBTL1ALDH1A1ATM | |
| SCHEMBL27704159 | 0.75 | KDM4E (0.60) | KDM4ENPC1L3MBTL1ALDH1A1ATM | |
| SCHEMBL2490016 | 0.75 | HCAR3 (0.60) | KDM4ENPC1L3MBTL1FGFR1HPGD | |
| SCHEMBL165333 | 0.74 | SMN1; SMN2 (0.71) | KDM4ENPC1L3MBTL1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193869-B | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA | 2011-03-02 | — | — | CN | disclosed |
| CN-101193869-A | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-04 | — | — | CN | disclosed |